2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996-1995 | 1994-1992 | 1991-1987 |
Hummel MA, Locuson CW, Gannett PM, Rock DA, Mosher C, Rettie AE, Tracy TS. CYP2C9 Genotype-Dependent Effects on In Vitro Drug-Drug Interactions: Switching of Benzbromarone Effect from Inhibition to Activation in the CYP2C9.3 Variant. Mol Pharm, 68:644-651, 2005.
Bland TM, Haining RL, Tracy TS, Callery PS. CYP2C-catalyzed delta(9)-Tetrahydrocannabinol Metabolism: Kinetics, Pharmacogenetics and Interaction with Phenytoin, Biochem Pharmacol, 70:1096-1103, 2005.
Kotlyar M, Brauer L, Tracy TS, Hatsukami DK, Harris J, Bronars CA, Adson DE. Inhibition of CYP2D6 activity by bupropion. J Clin Psychopharmacol, 25:226-229, 2005.
Kolwankar D, Glover DD, Ware JA, Tracy TS. Expression and Function of ABCB1 and ABCG2 in Human Placental Tissue, Drug Metab Dispos, 33:524-529, 2005.
Tracy TS, Venkataramanan R, Glover DD, Caritis SN. Temporal Changes in Drug Metabolism (CYP1A2, CYP2D6 and CYP3A Activity) During Pregnancy. Am J Obstet Gynecol, 192:633-639, 2005.
Locuson CW, Gannett PM, Ayscue R, Tracy TS. Use of simple docking methods to screen a virtual library for
heteroactivators of cytochrome P450 2C9. J Med Chem. 2007 Mar 22;50(6):1158-65.
Tirumalai PS, Gannett PM, Callery PS, Bland TM, Tracy TS. Conversion of Methamphetamine to N-Methyl-Methamphetamine in Formalin Solutions. J Anal Toxicol, 29:48-53, 2005.
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Williams ML, Mager DE, Parenteau H, Gudi G, Tracy TS, Mulheran M, Wainer IW. Effects of Protein Calorie Malnutrition on the Pharmacokinetics of Ketamine in Rats. Drug Metab Dispos, 32:786-793, 2004.
Hummel MA, Gannett PM, Aguilar JS, Tracy TS. Effector-Mediated Alteration of Substrate Orientation in Cytochrome P450 2C9. Biochemistry, 43:7207-7214, 2004.
Tracy TS, Hummel, MA. Modeling Kinetic Data from In Vitro Drug Metabolism Enzyme Experiments. Drug Metab Rev, 36:231-242, 2004.
Hummel MA, Dickmann LJ, Rettie AE, Haining RL, Tracy TS. Differential Activation of CYP2C9 Variants by Dapsone. Biochem Pharmacol, 67:1831-1841, 2004.
Komoroski BJ, Zhang S, Cai H, Hutzler JM, Frye R, Tracy TS, Strom SC, Lehmann T, Ang CYW, Cui YY, Venkataramanan R. Induction And Inhibition Of Cytochromes P450 By The St. John's Wort Constituent Hyperforin In Human Hepatocyte Cultures. Drug Metab Dispos, 32:512-518, 2004.
Glover DD, Rybeck BF, Tracy TS. Medication Use in a Rural Gynecologic Population: Prescription, Over-the Counter, and Herbal Medicines. Am J Obstet Gynecol, 190: 57-63, 2004.
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Belldina EB, Huang MY, Schneider JA, Brundage RC, Tracy TS. Steady-State Pharmacokinetics and Pharmacodynamics of Cysteamine Bitartrate in Pediatric Nephropathic Cystinosis Patients, Br J Clin Pharmacol, 56: 520-525, 2003.
Tracy TS. Atypical Enzyme Kinetics: Their Effect on In Vitro-In Vivo Pharmacokinetic Predictions and Drug Interactions, Curr Drug Metab, 4: 341-346, 2003.
Glover DD, Amonkar M, Rybeck BF, Tracy TS. Prescription, over-the-counter and alternative medicine use in a rural, obstetric population. Am J Obstet Gynecol, 188:1039-1045, 2003.
Gannett PM, Johnson EM, Grimes M, Myers A, Deavers RE, Tracy TS. Synthesis of deuterated 4,4’-diaminodiphenylsulfone (dapsone) and analogs. J Labelled Comp Radiopharm, 46:107-114, 2003.
Hutzler JM, Wienkers LC, Wahlstrom JL, Carlson TJ, Tracy TS. Activation of Cytochrome P450 2C9-Mediated Metabolism: Mechanistic Evidence in Support of Kinetic Observations. Arch Biochem Biophys, 410:16-24, 2003.
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Hutzler JM, Kolwankar D, Hummel MA, Tracy TS. Activation of CYP2C9-mediated metabolism by a series of dapsone analogs: Kinetics and structural requirements. Drug Metab Dispos, 30:1194-1200, 2002.
Hutzler JM, Tracy TS. Atypical Kinetic Profiles in Drug Metabolism Reactions. Drug Metab Dispos, 30:355-362, 2002.
Tracy TS, Hutzler JM, Haining RL, Rettie AE, Hummel MA, Dickmann LJ. Polymorphic variants (CYP2C9*3 and CYP2C9*5) and the F114L active site mutation of CYP2C9: Effect on atypical kinetic metabolism profiles. Drug Metab Dispos, 30:385-390, 2002.
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Gannett PM, Daft JR, James D, Rybeck BF, Knopp JB, Tracy TS. In vitro reaction of barbiturates with formaldehyde. J Anal Toxicol, 25: 443-449, 2001.
Tracy TS, Rybeck BF, James DG, Knopp JB, Gannett PM. Stability of benzodiazepines in formaldehyde solutions. J. Anal Toxicol, 25: 166-173, 2001.
Hutzler JM, Frye RF, Korzekwa KR, Branch RA, Huang S-M, Tracy TS. Minimal in vivo activation of CYP2C9-mediated flurbiprofen metabolism by dapsone. Eur J Pharmaceut Sci, 14: 47-52, 2001.
Hutzler JM, Hauer MJ, Tracy TS. Dapsone activation of CYP2C9-mediated metabolism: Evidence for activation of multiple substrates and a two-site model. Drug Metab Dispos, 29: 1029-1034, 2001.
Gannett PM, Hailu S, Daft J, James D, Rybeck B, Tracy TS. In vitro reaction of formaldehyde with fenfluramine: Conversion to N-methyl fenfluramine. J Anal Toxicol, 25: 88-92, 2001.
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Menke ER, Jackson CR, Bagby MD, Tracy TS. The effectiveness of prophylactic etodolac on post-endodontic pain. J Endodont, 26: 712-715, 2000.
Ko JW, Desta Z, Soukhova NV, Tracy T, Flockhart DA. In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6. Br J Clin Pharmacol, 49: 343-351, 2000.
Scharman EJ, Hutzler JM, Rosencrance JG, Tracy TS. Single dose pharmacokinetics of syrup of ipecac. Ther Drug Mon, 22: 566-573, 2000.
Hutzler JM, Frye RF, Tracy TS. Sensitive and specific high-performance liquid chromatographic Assay for 4'-hydroxyflurbiprofen and flurbiprofen in human urine and plasma. J Chromatogr B, 749: 119-125, 2000.
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Zhang W, Parenteau H, Greenly RL, Metz CA, Aggarwal S, Wainer IW, Tracy TS. Effect of protein-calorie malnutrition on cytochromes P450 and glutathione S-transferase. Eur J Drug Metab Pharmacokinet, 24: 141-147, 1999.
Schmidt RJ, Domico J, Samsell LS, Yokota S, Tracy TS, Sorkin MI, Engels K, Baylis C. Indices of activity of the nitric oxide system in patients on hemodialysis, Am J Kidney Dis, 34: 228-234, 1999.
Tracy TS, Korzekwa KR, Gonzalez FJ, Wainer IW. Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil. Br J Clin Pharmacol, 47: 545-552, 1999.
Schmidt RJ, Yokota S, Tracy TS, Sorkin MI, Baylis C. Nitric oxide production is low in end stage renal disease patients on peritoneal dialysis, Am J Physiol, 276 (Renal Physiol. 45):F794-F797, 1999.
Stamatakis MK, Leader WG, Tracy TS. Stability of high-dose vancomycin and ceftazidime in peritoneal dialysis solution. Am J Health-Syst Pharm, 56: 246-248, 1999.
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Korzekwa KR, Krishnamachary N, Shou M, Ogai, A, Parise RA, Rettie AE, Gonzalez FJ, Tracy TS. Evaluation of atypical cytochrome P450 kinetics with two-substrate-models: Evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites. Biochemistry, 37:4137-4147, 1998.
Cupp MJ, Tracy TS. Cytochrome P450: New Nomenclature-Clinical Implications, Am Fam Phys, 57: 107-116, 1998.
McRobie DJ, Glover DD, Tracy TS. Effects of gestational and overt diabetes on human placental cytochromes P450 and glutathione S-transferase. Drug Metab Dispos, 26: 367-371, 1998.
Omar HA, Ramirez R, Arsich J, Tracy T, Glover D, Gibson M. Reduction of the human placental vascular relaxation to progesterone by gestational diabetes. J Maternal-Fetal Invest, 8: 27-30, 1998.
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McRobie DJ, Korzekwa KR, Glover DD, Tracy TS. The effects of diabetes on placental aromatase activity. J Steroid Biochem Mol Biol, 63: 147-153, 1997.
Tracy TS, Marra C, Wrighton SA, Gonzalez FJ, Korzekwa KR. Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation. Eur J Clin Pharmacol, 52: 293-298, 1997.
Chittur SV, Tracy TS. A rapid and sensitive HPLC assay for 6-hydroxychlorzoxazone and chlorzoxazone in liver microsomes. J Chromatogr B - Biomed Appl, 693: 479-483, 1997.
Cupp M, Tracy TS. Role of the cytochrome P450 3A subfamily in drug interactions. US Pharmacist, January issue:HS9-HS21, 1997.
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McRobie DJ, Glover DD, Tracy TS. Regiospecificity of placental metabolism by cytochromes P450 and glutathione S-transferase. Gynecol Obstet Invest, 42:154-158, 1996.
Tracy TS, Marra C, Wrighton SA, Gonzalez FJ, Korzekwa KR. Studies of flurbiprofen 4’-hydroxylation: Additional evidence suggesting the sole involvement of cytochrome P450 2C9. Biochem Pharmacol, 52:1305-1309, 1996.
Tracy TS, Rosenbluth BW, Wrighton SA, Gonzalez FJ, Korzekwa KR. Role of cytochrome P450 2C9 and an allelic variant in the 4'-hydroxylation of (R)- and (S)-flurbiprofen. Biochem Pharmacol, 49:1269-1275, 1995.
Tracy TS. Stereochemistry in Pharmacotherapy: When mirror images are not identical. Annals of Pharmacotherapy, 29:161-165, 1995.
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Tracy TS, Worster T, Bradley JD, Greene PK, Brater DC. Methotrexate disposition following concomitant administration of ketoprofen, piroxicam and flurbiprofen in patients with rheumatoid arthritis. Br J Clin Pharmacol, 37:453-456, 1994.
Tracy TS, Hall SD. Metabolic inversion of (R)-ibuprofen: Formation of ibuprofenyl-coenzyme A. Drug Metab Disp, 21:114-120, 1993.
Tracy TS, Black CD. Ability of nifedipine to prolong parturition in rats. J Reprod Fertil 95:139-144, 1992.
Tracy TS, Hall SD. Metabolic inversion of (R)-ibuprofen: Epimerization and hydrolysis of ibuprofenyl-coenzyme A. Drug Metab Disp 20:322-327, 1992.
Tracy TS, Krohn K, Jones DR, Bradley JD, Hall SD, Brater DC. The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis. Eur J Clin Pharmacol, 42:121-125,1992.
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Tracy TS, Hall SD. Determination of the epimeric composition of ibuprofenyl-CoA. Analytical Biochem, 195:24-29, 1991.
Newton GD, Tracy TS, Popovich NG. The development and implementation of an integrating pharmacy practice laboratory. Am J Pharm Educ 54:138-145, 1990.
Tracy TS, Bowman L, Black CD. Effect of a partial PVC-based intravenous administration set on the delivery of nitroglycerin. Am J Hosp Pharm 46:2031-2035, 1989.
Tracy TS, Black CD. Calcium modulators: Future agents, future uses. Drug Intell Clin Pharm 21:575-583, 1987.
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